Analytical Technology
This course focuses on the available analytical and bioinformatics high-throughput platforms, and its application to pharmacogenomics. In brief, the candidate will learn the analytical basis of omic procedures employed in pharmacogenomics, to process and mine the analytical data, and to transfer it to clinicians and pharmacists to personalize patient treatments. During the course candidates will also learn to design new omic analyses in drug discovery environments, and to apply state-of-the-art methodologies to phenotype patients under several pathologies.
Teaching methods
• Lectures
• Practical sessions
- Course CodeOPPM 301
- ModuleModule 3
- Credit Hours10ECTS/3EG/3LB
- Understand the analytical basis of most of the high-throughput methodologies employed in pharmacogenomics.
- Differentiate the different analytical platforms employed in omics assay.
- Choose the appropriate analytical platforms for specific pharmacogenomics procedures (genotyping, splicing variants, enzymatic assays, pharmacokinetic assays, …)
- Process raw data coming from transcriptomics, genomics, proteomics or metabolomics platforms.
- Design custom pharmacogenomic analytical procedures.
- Employ omics data to evaluate and personalize patient treatments.
- Realize the role of sex and ethnicity on drug-response and its importance when applying pharmacogenomic algorithms.
- Create new links between hospital pharmacy and laboratory to provide precision treatments for individual patients.